Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Permethrin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | ADRA2A | P08913 | 1/20 | 1.00 |
| ▸ | CNR1 | P21554 | 1/20 | 1.00 |
| ▸ | ATM | Q13315 | 1/20 | 1.00 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.45 |
| ▸ | MMP1 | P03956 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP12 | P39900 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Permethrin SCHEMBL29397229 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL29442911 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9665188 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9669087 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL117908 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL910678 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL24089572 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL9754130 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL26543 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM | |
| Permethrin SCHEMBL121233 | 1.00 | TDP1 (1.00) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 608 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240224991-A9 | NANO-DISPERSION COMPRISING CELLULOSE NANOCRYSTAL AS PESTICIDE/FUNGICIDE CARRIERS FOR AGRICULTURE AND AQUACULTURE | TAM MICHAEL KAM CHIU (CA) | 2024-07-11 | — | — | US | claimed |
| US-20240130360-A1 | NANO-DISPERSION COMPRISING CELLULOSE NANOCRYSTAL AS PESTICIDE/FUNGICIDE CARRIERS FOR AGRICULTURE AND AQUACULTURE | TAM MICHAEL KAM CHIU (CA) | 2024-04-25 | — | — | US | claimed |
| EP-4337015-A1 | INSECT, ACARINA AND NEMATODE PEST CONTROL | Syngenta Crop Protection AG (CH) | 2024-03-20 | — | — | EP | claimed |
| EP-4337016-A1 | SEED TREATMENT COMPOSITIONS | Syngenta Crop Protection AG (CH) | 2024-03-20 | — | — | EP | claimed |
| CN-117320552-A | Insect, acarina and nematode pest control | 先正达农作物保护股份公司 | 2023-12-29 | — | — | CN | claimed |
| CN-117320551-A | Seed treatment composition | 先正达农作物保护股份公司 | 2023-12-29 | — | — | CN | claimed |
| EP-4294185-A1 | INSECT AND ACARINA PEST CONTROL | Syngenta Crop Protection AG (CH) | 2023-12-27 | — | — | EP | claimed |
| CN-116916751-A | Insect and acarina pest control | 先正达农作物保护股份公司 | 2023-10-20 | — | — | CN | claimed |
| WO-2023105064-A1 | INSECT, ACARINA AND NEMATODE PEST CONTROL | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-15 | — | — | WO | claimed |
| WO-2023105065-A1 | INSECT, ACARINA AND NEMATODE PEST CONTROL | SYNGENTA CROP PROTECTION AG (CH) | 2023-06-15 | — | — | WO | claimed |
| EP-0562164-A1 | Emulsifier-free water dilutable concentrate or agent for preserving wood and woody materials | DESOWAG GmbH (DE) | 1993-09-29 | — | — | EP | claimed |
| EP-0322820-B1 | USE OF A MICROENCAPSULATED COMPOSITON FOR THE CONTROL OF COCKROACHES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-04-07 | — | — | EP | claimed |
| EP-0458061-A1 | Agent for preserving wood and wooden materials | DESOWAG GmbH (DE) | 1991-11-27 | — | — | EP | claimed |
| EP-0458060-A1 | Agent for preserving wood and wooden materials | DESOWAG GmbH (DE) | 1991-11-27 | — | — | EP | claimed |
| EP-0385076-A1 | Agent or concentrate for the preservation of wood or wooden materials | DESOWAG Materialschutz GmbH (DE) | 1990-09-05 | — | — | EP | claimed |
| EP-0053100-B1 | PESTICIDE AGENTS | CIBA-GEIGY AG (CH) | 1984-09-19 | — | — | EP | claimed |
| EP-0001809-B1 | SYNERGETIC INSECTICIDAL AND ACARICIDAL MIXTURES | BASF Aktiengesellschaft (DE) | 1982-02-03 | — | — | EP | claimed |
| US-4297370-A | SYNERGISTIC MIXTURE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1981-10-27 | — | — | US | claimed |
| US-4153445-A | A MORPHOLINIUM OR PIPERIDINIUM SALT, SUBSTITUTED CYCLOPROPYL ESTEROF 3-PHENOXYBENZYL CARBOXYLIC ACID | BASF AKTIENGESELLSCHAFT (DE) | 1979-05-08 | — | — | US | claimed |
| US-4100297-A | CHRYSANTHEMIC ACID DERIVATIVES | ROUSSEL UCLAF (FR) | 1978-07-11 | — | — | US | claimed |