Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10591655 | 0.84 | ALDH1A1 (0.43) | KDM4EHPGDADORA1ADORA2AALDH1A1 | |
| SCHEMBL27425531 | 0.83 | GAA (0.45) | KDM4EHPGDIDO1ADORA1ADORA2A | |
| SCHEMBL9336031 | 0.78 | MAPK14 (0.39) | KDM4EHPGDNPSR1IDO1ALDH1A1 | |
| SCHEMBL1180128 | 0.77 | ALDH1A1 (0.39) | KDM4EHPGDIDO1ADORA1ADORA2A | |
| SCHEMBL10591516 | 0.77 | KIF11 (0.45) | KDM4ERXFP1ADORA1ALDH1A1GAA | |
| SCHEMBL13858869 | 0.76 | ALDH1A1 (0.46) | KDM4EHPGDNPSR1RXFP1IDO1 | |
| SCHEMBL21529737 | 0.76 | POLB (0.47) | KDM4EHPGDNPSR1ADORA1ADORA2B | |
| SCHEMBL116957 | 0.76 | ALDH1A1 (0.46) | KDM4EHPGDNPSR1RXFP1IDO1 | |
| SCHEMBL27425532 | 0.75 | CUL4A (0.37) | KDM4EHPGDADORA1ADORA2BADORA2A | |
| SCHEMBL9389357 | 0.74 | KIF11 (0.35) | KDM4EHPGDALDH1A1GAAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0746979-B1 | Use of pyrrole compounds as antifouling agents | BASF AG (DE) | 2004-07-21 | — | — | EP | claimed |
| US-5932520-A | FOR MARINE SURFACES | AMERICAN CYANAMID COMPANY (US) | 1999-08-03 | — | — | US | claimed |
| EP-0746979-A1 | Use of pyrrole compounds as antifouling agents | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | claimed |
| EP-3231283-A1 | BIOCIDE COMPOSITION COMPRISING ZINC PYRITHIONE AND A PYRROLE DERIVATIVE | Arch Chemicals, Inc. (US) | 2017-10-18 | — | — | EP | disclosed |
| US-8481523-B2 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. (US) | 2013-07-09 | — | — | US | disclosed |
| US-8372829-B2 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. (US) | 2013-02-12 | — | — | US | disclosed |
| US-20110143153-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110144232-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-06-16 | — | — | US | disclosed |
| US-20110104375-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2011-05-05 | — | — | US | disclosed |
| US-7893047-B2 | comprising zinc pyrithione, and 4-bromo-2-(4-chlorophenyl)-5-(trifluoromethyl)-1H-pyrrole-3-carbonitrile, present in a weight ratio of 3:2 to 2:3, and wherein biocidal composition is copper free or has low copper content | ARCH CHEMICALS, INC. (US) | 2011-02-22 | — | — | US | disclosed |
| US-20070207178-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | ARCH CHEMICALS, INC. | 2007-09-06 | — | — | US | disclosed |
| EP-0746979-B1 | Use of pyrrole compounds as antifouling agents | BASF AG (DE) | 2004-07-21 | — | — | EP | disclosed |
| US-5932520-A | FOR MARINE SURFACES | AMERICAN CYANAMID COMPANY (US) | 1999-08-03 | — | — | US | disclosed |
| EP-0746979-A1 | Use of pyrrole compounds as antifouling agents | American Cyanamid Company (US) | 1996-12-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070207178-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | PYCR1, CAT, BBOX1 | KDM4E 3108/4885HPGD 608/4885NPSR1 3467/4885 |
| US-20110144232-A1 | Biocide composition comprising pyrithione and pyrrole derivatives | PYCR1, CAT, BBOX1 | KDM4E 3108/4885HPGD 608/4885NPSR1 3467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.