Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.58 |
| ▸ | RECQL | P46063 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.58 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.58 |
| ▸ | APEX1 | P27695 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | CASP1 | P29466 | 2/20 | 0.58 |
| ▸ | CASP7 | P55210 | 2/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL116493 | 0.84 | MEN1 (0.67) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL10860655 | 0.82 | POLH (0.75) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL4286345 | 0.82 | MEN1 (0.65) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL119937 | 0.82 | MEN1 (0.61) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL34716 | 0.81 | KDM4E (0.73) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL29512814 | 0.81 | KDM4E (0.73) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL13056273 | 0.81 | POLH (0.58) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL13056267 | 0.80 | POLH (0.59) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| SCHEMBL7685645 | 0.78 | POLH (0.75) | MEN1KMT2AKDM4EMAPTHSD17B10 | |
| Fisetin SCHEMBL4466733 | 0.77 | MEN1 (0.90) | MEN1KMT2AKDM4EMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424541-A2 | PHOSPHORYLATED AND PHOSPHONATED PYRONE ANALOGS FOR THERAPEUTIC TREATMENT | Limerick BioPharma, Inc. (US) | 2012-03-07 | — | — | EP | disclosed |