Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23486625 | 0.86 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL13756101 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL23466483 | 0.83 | ALDH1A1 (0.53) | GPR35ALDH1A1LMNAMEN1HTT | |
| SCHEMBL11581199 | 0.82 | GPR35 (0.53) | GPR35ALDH1A1LMNAMEN1HTT | |
| SCHEMBL4342270 | 0.82 | ALDH1A1 (0.58) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL400049 | 0.80 | KCNMA1 (0.64) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL405736 | 0.79 | ALDH1A1 (0.55) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL12354957 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL3020364 | 0.77 | L3MBTL1 (0.60) | ALDH1A1LMNAMEN1HTTKMT2A | |
| SCHEMBL11786623 | 0.76 | GAA (0.65) | GPR35ALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114728917-B | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-12-08 | — | — | CN | disclosed |
| CN-114728917-A | Oxamide derivative, preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| US-3987192-A | ANTIALLERGENS AND ANTIANAPHYLAXID; 2'-CYANO-OXANILIC ACID | THE UPJOHN COMPANY (US) | 1976-10-19 | — | — | US | disclosed |