SCHEMBL11798570

SCHEMBL11798570

C=C1C=CCC2C(=O)N(C(C)C)C(=O)C12

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528994 0.78 ACHE (0.33)
SCHEMBL12308314 0.77 NPSR1 (0.46) SMN1; SMN2
SCHEMBL11584760 0.74 ALDH1A1 (0.38)
SCHEMBL17863545 0.73 SMN1; SMN2 (0.40) SMN1; SMN2
SCHEMBL11583580 0.72 ATM (0.35)
SCHEMBL11594146 0.70 GAA (0.33)
SCHEMBL11798562 0.70 NPSR1 (0.45)
SCHEMBL11528866 0.70 ALDH1A1 (0.37) SMN1; SMN2
SCHEMBL11529894 0.70 SMN1; SMN2 (0.40) SMN1; SMN2
SCHEMBL11594278 0.69 CNR2 (0.43) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3959234-A CATALYSTS OF ORGANOALUMINUM COMPOUNDS AND A TUNGSTEN OR MOLYBDENUM COMPOUND, RING-OPENING SHOWA DENKO KABUSHIKI KAISHA (JA) 1976-05-25 US disclosed