Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12308314 | 0.86 | NPSR1 (0.46) | SMN1; SMN2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL17863555 | 0.75 | SMN1; SMN2 (0.34) | SMN1; SMN2ALDH1A1KMT2ACYP3A4HPGD | |
| SCHEMBL11798570 | 0.73 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL14727214 | 0.70 | ALDH1A1 (0.41) | SMN1; SMN2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL17532424 | 0.69 | ALDH1A1 (0.45) | SMN1; SMN2NPSR1ALDH1A1LMNAHSD17B10 | |
| SCHEMBL676110 | 0.66 | NPSR1 (0.50) | SMN1; SMN2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL2661927 | 0.66 | NPSR1 (0.50) | SMN1; SMN2NPSR1ALDH1A1TSHRLMNA | |
| SCHEMBL13684329 | 0.66 | CYP19A1 (0.33) | SMN1; SMN2ALDH1A1KMT2AHPGDMAPT | |
| SCHEMBL17736731 | 0.66 | CYP19A1 (0.33) | SMN1; SMN2ALDH1A1KMT2AHPGDMAPT | |
| SCHEMBL1146669 | 0.66 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1TSHRLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160175829-A1 | CATALYST SYSTEMS FOR USE IN CONTINUOUS FLOW REACTORS AND METHODS OF MANUFACTURE AND USE THEREOF | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160175829-A1 | CATALYST SYSTEMS FOR USE IN CONTINUOUS FLOW REACTORS AND METHODS OF MANUFACTURE AND USE THEREOF | TKFC, F2, PICALM | SMN1; SMN2 2053/4885NPSR1 3615/4885ALDH1A1 1909/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.