Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | VDR | P11473 | 2/20 | 0.47 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10358233 | 0.82 | KIF11 (0.45) | KIF11MEN1KMT2APOLBVDR | |
| SCHEMBL28363827 | 0.81 | AHR (0.59) | KIF11MEN1KMT2APOLBAHR | |
| SCHEMBL10114729 | 0.80 | MLKL (0.46) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL10114753 | 0.79 | MLKL (0.45) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL28201526 | 0.78 | AHR (0.55) | KIF11MEN1KMT2APOLBAHR | |
| SCHEMBL262221 | 0.78 | KIF11 (0.77) | KIF11MEN1KMT2ANPC1POLB | |
| Carbazole SCHEMBL28016320 | 0.78 | KIF11 (0.77) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL29563317 | 0.78 | KIF11 (0.77) | KIF11MEN1KMT2ANPC1POLB | |
| SCHEMBL11846487 | 0.76 | AHR (0.57) | KIF11MEN1KMT2AVDRAHR | |
| SCHEMBL11798982 | 0.76 | VDR (0.66) | MEN1KMT2APOLBVDRAHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217297-B2 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | claimed |
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-09-30 | — | — | US | claimed |
| EP-1437122-A1 | Composition for dyeing keratinic fibers comprising a diheteroarylmethane direct dye or its lecuco precursor and dyeing process using this composition | L'OREAL (FR) | 2004-07-14 | — | — | EP | claimed |
| EP-1437122-B1 | Composition for dyeing keratinic fibers comprising diheteroarylmethane direct dye and dyeing process using this composition | OREAL (FR) | 2010-03-03 | — | — | EP | disclosed |
| US-7217297-B2 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2007-05-15 | — | — | US | disclosed |
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | L'OREAL S.A. (FR) | 2004-09-30 | — | — | US | disclosed |
| EP-1437122-A1 | Composition for dyeing keratinic fibers comprising a diheteroarylmethane direct dye or its lecuco precursor and dyeing process using this composition | L'OREAL (FR) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040187229-A1 | Composition for dyeing keratin fibers comprising a defined diheteroylarylmethane direct dye or a leuco precursor of this dye and dyeing method using it | KRT18, KMO, DLD | KIF11 417/4885MEN1 4265/4885KMT2A 273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.