Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.61 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | SHBG | P04278 | 4/20 | 0.61 |
| ▸ | SERPINA6 | P08185 | 4/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | BLM | P54132 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.61 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | PGR | P06401 | 3/20 | 0.58 |
| ▸ | DRD1 | P21728 | 1/20 | 0.58 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931094 | 0.84 | HIF1A (0.64) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL10705465 | 0.83 | CYP3A4 (0.60) | NR3C1LMNASHBGCYP2C19MAPT | |
| SCHEMBL11799696 | 0.83 | CYP3A4 (0.60) | NR3C1LMNASHBGCYP2C19MAPT | |
| SCHEMBL3940208 | 0.82 | NR3C1 (0.48) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL10703752 | 0.81 | NR3C1 (0.62) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL3777666 | 0.80 | LMNA (0.67) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL3029696 | 0.80 | LMNA (0.67) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL3777671 | 0.80 | LMNA (0.67) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL10707185 | 0.80 | NR3C1 (0.46) | NR3C1LMNASHBGSERPINA6CYP2C19 | |
| SCHEMBL10703308 | 0.80 | AR (0.54) | NR3C1LMNASHBGSERPINA6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937700-A | Novel 1,2-methylene-17α-acyloxy (or improved hydroxy)-9β, 10α-steroid compounds of the pregnane series, pharmaceutic preparations on the basis of the novel compounds and methods of producing said compounds and preparations | U.S. PHILIPS CORPORATION (US) | 1976-02-10 | — | — | US | disclosed |