Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27588220 | 0.86 | KDM4E (0.53) | KDM4EHPGDALDH1A1MAPTMEN1 | |
| SCHEMBL12306715 | 0.82 | KDM4E (0.57) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL28560255 | 0.82 | ALDH1A1 (0.54) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL15147200 | 0.81 | KEAP1 (0.51) | KDM4EHPGDPARP1ADORA2A | |
| SCHEMBL11296815 | 0.81 | KDM4E (0.55) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL7570255 | 0.80 | KDM4E (0.42) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL27550693 | 0.78 | DHFR (0.52) | KDM4EHPGDTDP1MAPT | |
| SCHEMBL18593568 | 0.78 | KDM4E (0.73) | KDM4EHPGDALDH1A1POLBHSD17B10 | |
| SCHEMBL10729268 | 0.77 | ALDH1A1 (0.40) | KDM4EHPGDALDH1A1HSD17B10ALOX15 | |
| SCHEMBL7575228 | 0.76 | KDM4E (0.64) | KDM4EHPGDALDH1A1POLBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4000101-A | POLYPROPYLENE | WESTON CHEMICAL CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3959220-A | Polymer additives comprising transition metal complexes with trivalent phosphorous compounds | CINCINNATI MILACRON CHEMICALS, INC. (US) | 1976-05-25 | — | — | US | disclosed |