Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11675996 | 0.88 | KDM4E (0.64) | KDM4EHPGDHTTTDP1ALDH1A1 | |
| SCHEMBL11132652 | 0.85 | KDM4E (0.59) | KDM4EHPGDHTTALDH1A1POLB | |
| SCHEMBL28560255 | 0.83 | ALDH1A1 (0.54) | KDM4EHPGDHTTTDP1ALDH1A1 | |
| SCHEMBL11799485 | 0.81 | KDM4E (0.50) | KDM4EHPGDHTTTDP1ALDH1A1 | |
| SCHEMBL29216527 | 0.79 | MAPT (0.53) | KDM4EHPGDHTTTDP1CA2 | |
| SCHEMBL7570255 | 0.77 | KDM4E (0.42) | KDM4EHPGDHTTTDP1ALDH1A1 | |
| SCHEMBL27622563 | 0.77 | KDM4E (0.59) | KDM4EHPGDHTTALDH1A1MAPT | |
| SCHEMBL29061455 | 0.76 | FAAH (0.50) | KDM4EHPGDHTTTDP1ALDH1A1 | |
| SCHEMBL77763 | 0.75 | LMNA (0.58) | KDM4EHPGDTDP1ALDH1A1POLB | |
| SCHEMBL29517159 | 0.75 | LMNA (0.58) | KDM4EHPGDTDP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57045169-A | — | — | None | — | — | JP | disclosed |
| JP-S5745169-A | BENZOTRIAZOLE COMPOUND AND ITS PREPARATION | ASAHI GLASS CO LTD | 1982-03-13 | — | — | JP | disclosed |