Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 3/20 | 0.40 |
| ▸ | EPM2A | O95278 | 1/20 | 0.40 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | SENP5 | Q96HI0 | 2/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17173230 | 0.84 | MCL1 (0.48) | EDNRAPTPN1PTPN2GPR35SENP5 | |
| SCHEMBL6995489 | 0.83 | EDNRA (0.54) | EDNRAPTPN1PRNPCYP1A2PPARG | |
| SCHEMBL15697543 | 0.81 | EDNRA (0.44) | EDNRAPTPN1PTPN2SENP5SENP2 | |
| SCHEMBL15697532 | 0.80 | PTPN2 (0.56) | EDNRAPTPN1PTPN2SENP5SENP2 | |
| SCHEMBL11799095 | 0.79 | SENP5 (0.44) | EDNRASENP5SENP2SENP1CYP1A2 | |
| SCHEMBL11794869 | 0.76 | ICAM1 (0.38) | CA12CA9NPSR1RXFP1SMN1; SMN2 | |
| SCHEMBL11794862 | 0.76 | GLA (0.53) | CYP1A2CYP2C9NPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2896475 | 0.76 | GPR35 (0.58) | PTPN1PTPN2EPM2APTPN22GPR35 | |
| SCHEMBL20563613 | 0.76 | MCL1 (0.60) | PTPN1PTPN2EPM2APTPN22GPR35 | |
| Bromomethane SCHEMBL11883047 | 0.75 | ICAM1 (0.37) | CA12CA9SENP5SENP2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976780-A | Methods of protection against emesis in mammals by administration of a 3-alkoxy-thianaphthene-2-carboxamide | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES L'ILE-DE-FRANCE (FR) | 1976-08-24 | — | — | US | disclosed |
| US-3954748-A | ANTIEMETICS | SOCIETE D'ETUDES SCIENTIFIQUES ET INDUSTRIELLES DE L'ILE-DE-FRANCE (FR) | 1976-05-04 | — | — | US | disclosed |