Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 7/20 | 0.53 |
| ▸ | TTR | P02766 | 5/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.43 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | COMT | P21964 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805184 | 0.90 | GSK3B (0.50) | GPR35TTRCA12CA1CA2 | |
| SCHEMBL11796921 | 0.81 | PDK1 (0.58) | GPR35TTRCRHBPCRHR2CA12 | |
| SCHEMBL11796885 | 0.81 | GPR35 (0.53) | GPR35TTRCRHBPCRHR2CA12 | |
| SCHEMBL11799907 | 0.80 | GPR35 (0.54) | GPR35TTRCA1CA2KDM4E | |
| SCHEMBL11808827 | 0.77 | GPR35 (0.56) | GPR35TTRCRHBPCRHR2CA12 | |
| SCHEMBL503443 | 0.76 | CASP6 (0.62) | GPR35TTRCRHBPCRHR2ALDH1A1 | |
| SCHEMBL11799406 | 0.76 | ERN1 (0.51) | GPR35TTRCRHBPCRHR2KDM4E | |
| SCHEMBL9064336 | 0.75 | CYP3A4 (0.59) | GPR35TTRCRHBPCRHR2CA12 | |
| SCHEMBL11799631 | 0.75 | GPR35 (0.61) | GPR35TTRCRHBPCRHR2CA12 | |
| SCHEMBL4893026 | 0.75 | GPR35 (0.69) | GPR35TTRCRHBPCRHR2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933472-A | Substituted alkylaryl ketones and methods of use as herbicides | BUCKMAN LABORATORIES, INC. (US) | 1976-01-20 | — | — | US | disclosed |