Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.64 |
| ▸ | DRD2 | P14416 | 6/20 | 0.64 |
| ▸ | HTR2A | P28223 | 5/20 | 0.64 |
| ▸ | HTR6 | P50406 | 5/20 | 0.64 |
| ▸ | HTR7 | P34969 | 4/20 | 0.64 |
| ▸ | HEXA | P06865 | 3/20 | 0.55 |
| ▸ | HEXB | P07686 | 3/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | RAD52 | P43351 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811153 | 0.86 | DRD2 (0.53) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11812209 | 0.83 | DRD2 (0.53) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11630716 | 0.81 | RAD52 (0.43) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11813960 | 0.78 | KDM4E (0.57) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11809762 | 0.78 | HTR1A (0.54) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11806115 | 0.77 | KDM4E (0.56) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11803485 | 0.76 | DRD2 (0.49) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11808412 | 0.76 | DRD2 (0.66) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11811501 | 0.75 | MEN1 (0.50) | HTR1ADRD2HTR2AHTR6HTR7 | |
| SCHEMBL11810045 | 0.74 | KDM4E (0.59) | HTR1ADRD2HTR2AHTR6HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |