Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HEXA | P06865 | 1/20 | 0.42 |
| ▸ | HEXB | P07686 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.39 |
| ▸ | PKLR | P30613 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11744846 | 0.87 | L3MBTL1 (0.51) | RAD52L3MBTL1KDM4EALDH1A1DRD2 | |
| SCHEMBL11741206 | 0.84 | L3MBTL1 (0.46) | RAD52L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL11633309 | 0.82 | RAD52 (0.49) | RAD52L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL11801300 | 0.81 | HTR1A (0.64) | RAD52POLBKDM4EALDH1A1HEXA | |
| SCHEMBL11630749 | 0.81 | L3MBTL1 (0.50) | RAD52L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL11632571 | 0.80 | L3MBTL1 (0.43) | RAD52L3MBTL1POLBKDM4EALDH1A1 | |
| SCHEMBL11631967 | 0.79 | L3MBTL1 (0.48) | L3MBTL1KDM4EALDH1A1DRD2HTR2A | |
| SCHEMBL11628469 | 0.78 | L3MBTL1 (0.47) | RAD52L3MBTL1POLBKDM4EKMT2A | |
| SCHEMBL11629858 | 0.78 | L3MBTL1 (0.44) | RAD52L3MBTL1POLBKDM4EKMT2A | |
| SCHEMBL11631256 | 0.77 | HTR1A (0.62) | L3MBTL1POLBKDM4EALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4077958-A | ANTIDEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |