Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11677519 | 0.83 | MMP2 (0.38) | TMEM97SIGMAR1KCNH2GRIN2DGRIN2A | |
| SCHEMBL11863353 | 0.79 | PTGS2 (0.33) | TMEM97SIGMAR1GRIN2DGRIN2AGRIN2B | |
| SCHEMBL11798128 | 0.78 | TRPV1 (0.37) | TMEM97SIGMAR1KCNH2 | |
| SCHEMBL11801336 | 0.76 | HDAC1 (0.38) | MAOAMAOBSLC6A2SLC6A4DRD2 | |
| SCHEMBL11550232 | 0.73 | CYP1A2 (0.50) | GRIN2DGRIN2AGRIN2BGRIN2CCYP2D6 | |
| SCHEMBL11797763 | 0.73 | SIGMAR1 (0.47) | SIGMAR1KCNH2SLC6A2SLC6A4DRD2 | |
| SCHEMBL30771503 | 0.71 | GRIN2D (0.37) | GRIN2DGRIN2AGRIN2BGRIN2CMAOA | |
| SCHEMBL11797647 | 0.71 | HPGD (0.41) | — | |
| SCHEMBL11832433 | 0.71 | KCNH2 (0.44) | KCNH2SLC6A2SLC6A4DRD2HTR2A | |
| SCHEMBL11818477 | 0.70 | MAOA (0.52) | MAOAMAOBSLC6A2SLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |