Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | TOP1 | P11387 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3661171 | 0.87 | TOP1 (0.57) | POLBNPC1RAB9AGAATOP1 | |
| SCHEMBL8777865 | 0.84 | HDAC1 (0.58) | TOP1TOP2ATOP2BMAPK1 | |
| SCHEMBL8844428 | 0.84 | NPC1 (0.65) | HPGDNPC1RAB9AGAATOP1 | |
| SCHEMBL9417251 | 0.83 | MEN1 (0.60) | HPGDNPC1RAB9AGAAALDH1A1 | |
| SCHEMBL2908808 | 0.82 | HPGD (0.79) | HPGDPOLBNPC1RAB9ATAS1R3 | |
| SCHEMBL15556976 | 0.81 | TOP1 (0.77) | HPGDPOLBNPC1RAB9ATAS1R3 | |
| SCHEMBL8777972 | 0.79 | TOP1 (0.48) | HPGDNPC1RAB9AGAATOP1 | |
| SCHEMBL7295495 | 0.78 | POLB (0.72) | HPGDPOLBNPC1RAB9AGAA | |
| SCHEMBL9979204 | 0.78 | TOP1 (0.51) | HPGDPOLBNPC1RAB9AGAA | |
| SCHEMBL9055150 | 0.77 | HPGD (0.89) | HPGDPOLBNPC1RAB9ATAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992434-A | Ethanol- and substituted ethanolamides of hindered 3,5-dialkyl-4-hydroxybenzoic acids | AMERICAN CYANAMID COMPANY (US) | 1976-11-16 | — | — | US | disclosed |
| US-3972927-A | Alkylamides of hindered 3,5-dialkyl-4-hydroxybenzoic acids and use as light stabilizers in polyolefins | AMERICAN CYANAMID COMPANY (US) | 1976-08-03 | — | — | US | disclosed |