SCHEMBL11802479

SCHEMBL11802479

CCC(=O)CCNc1cccc2c1C(=O)N=NC2=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.43
KMT2A Q03164 6/20 0.43
POLB P06746 4/20 0.43
NSD2 O96028 2/20 0.43
BLM P54132 2/20 0.43
RXFP1 Q9HBX9 1/20 0.43
FGB P02675 1/20 0.37
MMP14 P50281 1/20 0.37
CASP1 P29466 2/20 0.37
USP2 O75604 1/20 0.37
BRCA1 P38398 1/20 0.37
CASP7 P55210 1/20 0.37
MAPT P10636 4/20 0.36
HPGD P15428 3/20 0.36
TERT O14746 8/20 0.36
ALDH1A1 P00352 4/20 0.34
MAPK1 P28482 2/20 0.34
HTT P42858 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
RAD52 P43351 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4955660 0.83 MEN1 (0.42) MEN1KMT2APOLBNSD2BLM
SCHEMBL4953462 0.79 MEN1 (0.55) MEN1KMT2APOLBNSD2BLM
SCHEMBL4956841 0.77 MAPT (0.59) MEN1KMT2APOLBMAPTHPGD
SCHEMBL4954956 0.76 NSD2 (0.41) MEN1KMT2APOLBNSD2BLM
SCHEMBL4956575 0.72 MAOA (0.59) HPGDALDH1A1HSD17B10GAA
SCHEMBL4958613 0.71 MAPT (0.55) MEN1KMT2APOLBBLMCASP1
SCHEMBL4958351 0.71 MAPT (0.34) MEN1KMT2ANSD2FGBMMP14
SCHEMBL4955900 0.71 ALDH1A1 (0.42) MEN1KMT2APOLBNSD2BLM
SCHEMBL4956713 0.70 MAPT (0.34) MEN1KMT2APOLBCASP1USP2
SCHEMBL23189083 0.70 MAPT (0.60) MEN1KMT2APOLBMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3933488-A CHEMILUMINESCENCE FUJI PHOTO FILM CO., LTD. (JA) 1976-01-20 US disclosed