Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TERT | O14746 | 8/20 | 0.47 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4956575 | 0.83 | MAOA (0.59) | HPGDHSD17B10ALDH1A1NPC1RAB9A | |
| SCHEMBL6366579 | 0.81 | TERT (0.68) | MAPTHPGDTERTALDH1A1MEN1 | |
| SCHEMBL4953462 | 0.78 | MEN1 (0.55) | MAPTHPGDTERTMAPK1ALDH1A1 | |
| SCHEMBL11802479 | 0.77 | MEN1 (0.43) | MAPTHPGDTERTALOX15MAPK1 | |
| SCHEMBL8602265 | 0.77 | MAOA (0.69) | MAPTHPGDTERTMAPK1ALDH1A1 | |
| SCHEMBL4958613 | 0.75 | MAPT (0.55) | MAPTHPGDTERTMAPK1HSD17B10 | |
| SCHEMBL4958351 | 0.75 | MAPT (0.34) | MAPTHPGDTERTALOX15MAPK1 | |
| SCHEMBL4955660 | 0.75 | MEN1 (0.42) | MAPTHPGDTERTMAPK1ALDH1A1 | |
| SCHEMBL5541192 | 0.75 | MAPT (0.62) | MAPTHPGDTERTALDH1A1MEN1 | |
| SCHEMBL4956713 | 0.75 | MAPT (0.34) | MAPTHPGDTERTALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968602-B2 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2018-05-15 | — | — | US | claimed |
| US-20140030317-A1 | MODULATION OF CELL FATES AND ACTIVITIES BY PHTHALAZINEDIONES | Occhiuti & Rohlicek LLP | 2014-01-30 | — | — | US | claimed |
| US-7326690-B2 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2008-02-05 | — | — | US | claimed |
| US-20070142303-A1 | Modulation of cell fates and activities by phthalazinediones | BACH PHARMA, INC. (US) | 2007-06-21 | — | — | US | claimed |