SCHEMBL11803167

SCHEMBL11803167

CCCC(C)(C)c1cc(C(C)(C)CC(C)(C)C)cc(C(C)(C)CC(C)(C)C)c1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.43
CYP3A4 P08684 4/20 0.38
HIF1A Q16665 2/20 0.38
ALDH1A1 P00352 2/20 0.38
IDH1 O75874 1/20 0.38
CYP2C9 P11712 1/20 0.38
ALOX15 P16050 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP2D6 P10635 1/20 0.35
CNR1 P21554 4/20 0.34
CNR2 P34972 3/20 0.34
NR5A2 O00482 1/20 0.33
NR5A1 Q13285 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
ESR1 P03372 6/20 0.33
ESR2 Q92731 4/20 0.33
AR P10275 2/20 0.33
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
TP53 P04637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19223388 0.90 SHBG (0.41) SHBGCYP3A4HIF1AALDH1A1IDH1
SCHEMBL767213 0.89 SHBG (0.52) SHBGCYP3A4HIF1AALDH1A1IDH1
SCHEMBL1835827 0.87 CNR2 (0.38) ALDH1A1CNR1CNR2NR5A2NR5A1
SCHEMBL11800941 0.86 SHBG (0.46) SHBGCYP3A4HIF1AALDH1A1IDH1
SCHEMBL11520878 0.85 SHBG (0.34) SHBGCYP3A4HIF1AALDH1A1CYP2C9
SCHEMBL11806573 0.84 CA2 (0.48) SHBGCYP3A4HIF1AALDH1A1IDH1
SCHEMBL11863309 0.81 GABBR2 (0.37) SHBGCYP3A4HIF1AALDH1A1CYP2C9
SCHEMBL1835022 0.80 CNR2 (0.46) CNR1CNR2NR5A2NR5A1ESR1
SCHEMBL8990196 0.80 SHBG (0.47) SHBGCYP3A4HIF1AALDH1A1IDH1
SCHEMBL6015498 0.80 CYP3A4 (0.51) SHBGCYP3A4HIF1AALDH1A1IDH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3959207-A PHENOLIC COMPOUNDS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-05-25 US disclosed