SCHEMBL8990196

SCHEMBL8990196

CC(C)(C)CC(C)(C)c1cc(-c2cc(C(C)(C)CC(C)(C)C)cc(C(C)(C)CC(C)(C)C)c2O)c(O)c(C(C)(C)CC(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.47
CYP3A4 P08684 4/20 0.41
HIF1A Q16665 2/20 0.41
IDH1 O75874 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41
HSD17B10 Q99714 1/20 0.41
CYP2D6 P10635 1/20 0.37
HSP90AA1 P07900 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
ESR1 P03372 1/20 0.34
TP53 P04637 1/20 0.34
PGR P06401 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
AR P10275 1/20 0.34
MAPT P10636 1/20 0.34
DRD1 P21728 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11189634 0.91 SHBG (0.46) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL767213 0.90 SHBG (0.52) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL11806573 0.85 CA2 (0.48) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL6015498 0.85 CYP3A4 (0.51) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL11800941 0.83 SHBG (0.46) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL28463799 0.81 SHBG (0.44) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL3820564 0.80 SHBG (0.43) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL11803167 0.80 SHBG (0.43) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL3232508 0.80 CA2 (0.52) SHBGCYP3A4HIF1AIDH1ALDH1A1
SCHEMBL28717515 0.80 IDH1 (0.34) SHBGCYP3A4HIF1AIDH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP claimed
EP-2797938-B1 METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2016-06-01 EP disclosed
EP-2797938-A1 METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2014-11-05 EP disclosed
US-8841474-B2 Process for preparing 6-chlorodibenzo[D,F][1,3,2]dioxaphosphepin BASF SE (DE) 2014-09-23 US disclosed
WO-2013098371-A1 METHOD FOR PRODUCING 6-CHLORODIBENZO [D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2013-07-04 WO disclosed
US-20130172596-A1 PROCESS FOR PREPARING 6-CHLORODIBENZO[D,F][1,3,2]DIOXAPHOSPHEPIN BASF SE (DE) 2013-07-04 US disclosed
EP-0509740-B1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KK (JP) 1996-06-26 EP disclosed
US-5262295-A Biphenyldihydroxide reducing agent for silver halide emulsion layers CANON KABUSHIKI KAISHA (JP) 1993-11-16 US disclosed
EP-0509740-A1 Heat-developable photosensitive material and image forming method making use of the heat-developable photosensitive material CANON KABUSHIKI KAISHA (JP) 1992-10-21 EP disclosed
EP-0032681-B1 HINDERED BIS-PHENOL PHENYL PHOSPHITES AND SYNTHETIC RESIN COMPOSITIONS HAVING ENHANCED STABILITY TO HEAT AND LIGHT ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1987-07-22 EP disclosed
EP-0035965-B1 PROCESS FOR THE PREPARATION OF 2.2'-DIHYDROXYBIPHENYL COMPOUNDS CIBA-GEIGY AG (CH) 1983-05-18 EP disclosed
US-4380676-A Process for the production of 2,2'-dihydroxy-biphenyls CIBA-GEIGY CORPORATION (US) 1983-04-19 US disclosed
US-4362830-A Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., LTD. (JP) 1982-12-07 US disclosed
EP-0035965-A2 Process for the preparation of 2.2'-dihydroxybiphenyl compounds CIBA-GEIGY AG (CH) 1981-09-16 EP disclosed
EP-0032681-A2 Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1981-07-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172596-A1 PROCESS FOR PREPARING 6-CHLORODIBENZO[D,F][1,3,2]DIOXAPHOSPHEPIN DCPS, PLCB3, DDT SHBG 4816/4885CYP3A4 628/4885HIF1A 3029/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.