SCHEMBL505769

SCHEMBL505769

CCC(CO)(CO)COC(=O)c1ccccc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.71
HIF1A Q16665 1/20 0.71
LMNA P02545 2/20 0.54
TDP1 Q9NUW8 4/20 0.54
SLC6A3 Q01959 2/20 0.54
CYP2D6 P10635 2/20 0.54
HTR1A P08908 1/20 0.54
SCN1A P35498 1/20 0.54
SCN5A Q14524 1/20 0.54
SCN2A Q99250 1/20 0.54
SCN3A Q9NY46 1/20 0.54
TSHR P16473 3/20 0.47
KMT2A Q03164 3/20 0.47
SLC6A2 P23975 1/20 0.47
ALDH1A1 P00352 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
CYP1A2 P05177 2/20 0.44
CYP2C19 P33261 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11436193 0.97 MAPK1 (0.71) MAPK1HIF1ALMNATDP1SLC6A3
SCHEMBL235921 0.93 MAPK1 (0.81) MAPK1HIF1ALMNATDP1SLC6A3
SCHEMBL1786754 0.91 MAPK1 (0.79) MAPK1HIF1ALMNATDP1SLC6A3
SCHEMBL6906425 0.91 MAPK1 (0.56) MAPK1HIF1ALMNATDP1SLC6A3
SCHEMBL9947121 0.91 MAPK1 (0.79) MAPK1HIF1ALMNATDP1SLC6A3
Methacrylic Acid SCHEMBL36396 0.91 MAPK1 (0.59) MAPK1HIF1ALMNATDP1SLC6A3
Acrylic Acid SCHEMBL57609 0.91 MAPK1 (0.59) MAPK1HIF1ALMNATDP1SLC6A3
Ethylene Glycol SCHEMBL17996173 0.90 MAPK1 (0.71) MAPK1HIF1ALMNATDP1SLC6A3
SCHEMBL12995220 0.90 MAPK1 (0.55) MAPK1HIF1ALMNATDP1SLC6A3
SCHEMBL2333610 0.90 MAPK1 (0.81) MAPK1HIF1ALMNATDP1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114656818-B metal oxide dispersion 凯斯科技股份有限公司 2023-11-17 CN claimed
CN-114656818-A Metal oxide dispersion 凯斯科技股份有限公司 2022-06-24 CN claimed
US-11319390-B2 Poly(ethylene glycol) methacrylate microgels, preparation method and uses LVMH RECHERCHE (FR) 2022-05-03 US claimed
US-20200377674-A1 POLY(ETHYLENE GLYCOL) METHACRYLATE MICROGELS, PREPARATION METHOD AND USES LVMH RECH (FR) 2020-12-03 US claimed
US-10799610-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2020-10-13 US claimed
US-10413632-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2019-09-17 US claimed
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2018-09-20 US claimed
US-9993576-B2 Cement products and methods of making and using the same PIONEER SURGICAL TECHNOLOGY, INC. (US) 2018-06-12 US claimed
EP-2192886-B1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME PIONEER SURGICAL TECH INC (US) 2017-12-20 EP claimed
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME MIDCAP FINANCIAL TRUST 2017-11-23 US claimed
EP-1675943-A4 NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF MASSACHUSETTS INST TECHNOLOGY (US) 2007-12-05 EP claimed
US-7262230-B2 Process of preparing crosslinked, low loss polymers with tunable refractive indices LUMERA CORPORATION (US) 2007-08-28 US claimed
US-20060167213-A1 Process of preparing crosslinked, low loss polymers with tunable refractive indices SILICON VALLEY BANK 2006-07-27 US claimed
EP-1675943-A2 NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF Massachusetts Institute of Technology (US) 2006-07-05 EP claimed
EP-1539344-A2 PRODUCTION OF POLYMERIC MICROARRAYS Massachusetts Institute Of Technology (US) 2005-06-15 EP claimed
WO-2005028619-A2 NANOLITER-SCALE SYNTHESIS OF ARRAYED BIOMATERIALS AND SCREENING THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2005-03-31 WO claimed
US-20050019747-A1 Nanoliter-scale synthesis of arrayed biomaterials and screening thereof NATIONAL INSTITUTES OF HEALTH 2005-01-27 US claimed
WO-2004043588-A2 PRODUCTION OF POLYMERIC MICROARRAYS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2004-05-27 WO claimed
US-20040028804-A1 Production of polymeric microarrays MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2004-02-12 US claimed
US-4218355-A Low organic solvent-containing polyester coating compositions PPG INDUSTRIES, INC. (US) 1980-08-19 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180264165-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT MAPK1 3407/4885HIF1A 594/4885LMNA 4535/4885
US-20170333594-A1 CEMENT PRODUCTS AND METHODS OF MAKING AND USING THE SAME BHMT2, SHMT1, BHMT MAPK1 3407/4885HIF1A 594/4885LMNA 4535/4885
US-10799610-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT MAPK1 3407/4885HIF1A 594/4885LMNA 4535/4885
US-10413632-B2 Cement products and methods of making and using the same BHMT2, SHMT1, BHMT MAPK1 3407/4885HIF1A 594/4885LMNA 4535/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.