Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337004 | 0.90 | ABCB1 (0.53) | ABCB1HTTTSHR | |
| SCHEMBL11342597 | 0.81 | TSHR (0.56) | ABCB1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11353654 | 0.80 | TSHR (0.57) | ABCB1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL8315378 | 0.76 | HTR1A (0.37) | ABCB1TSHR | |
| SCHEMBL16727483 | 0.75 | ABCB1 (0.75) | ABCB1HTTADRB2ADRB1ADRB3 | |
| SCHEMBL16727482 | 0.75 | ABCB1 (0.70) | ABCB1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11811055 | 0.73 | KDM4E (0.56) | — | |
| SCHEMBL1552388 | 0.72 | KDM4E (0.55) | ABCB1HTTTSHR | |
| SCHEMBL14076211 | 0.72 | LMNA (0.55) | ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11337007 | 0.72 | ALDH1A1 (0.53) | HTTADRB2ADRB1ADRB3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3962334-A | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxybenzil | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-08 | — | — | US | claimed |
| US-3962334-A | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxybenzil | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-06-08 | — | — | US | disclosed |
| US-3935191-A | Aminoalkyl ethers of 2,2'- and 3,3'-dihydroxybenzil | AMERICAN HOME PRODUCTS CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |