Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 12/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.55 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.55 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16727483 | 0.88 | ABCB1 (0.75) | ABCB1ADRB2ADRB1ADRB3TSHR | |
| SCHEMBL11337004 | 0.85 | ABCB1 (0.53) | ABCB1TSHR | |
| SCHEMBL7050989 | 0.81 | CYP1A2 (0.58) | ABCB1AGER | |
| SCHEMBL15344028 | 0.81 | KDM4E (0.54) | ABCB1TSHR | |
| SCHEMBL15539763 | 0.79 | ABCB1 (0.48) | ABCB1TSHRAGERPOLBNPSR1 | |
| SCHEMBL477006 | 0.78 | ALDH1A1 (0.59) | ABCB1TSHRAGER | |
| SCHEMBL21793185 | 0.78 | HIF1A (0.59) | ABCB1ADRB2ADRB1ADRB3 | |
| SCHEMBL13166873 | 0.77 | ABCB1 (0.54) | ABCB1ADRB2ADRB1 | |
| Propanol SCHEMBL524035 | 0.77 | KDM4E (0.51) | ABCB1TSHRAGER | |
| Bicarbonate SCHEMBL236893 | 0.76 | ALDH1A1 (0.57) | ABCB1ADRB1ADRB3TSHRAGER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSITÄT WIEN (AT) | 2016-11-03 | — | — | US | disclosed |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | MEDIZINISCHE UNIVERSTÄT WIEN (AT) | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160318887-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | ABCB1 1296/4885ADRB2 38/4885ADRB1 39/4885 |
| US-20150141437-A1 | AMIDOPHENOXYPROPANOLAMINES | ADH5, HRH3, PNMT | ABCB1 1296/4885ADRB2 38/4885ADRB1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.