Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 5/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11794930 | 0.82 | ALDH1A1 (0.45) | NPC1RAB9AALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL11797777 | 0.81 | ALDH1A1 (0.44) | NPC1RAB9AALDH1A1L3MBTL1MAPT | |
| Hydrochloric Acid SCHEMBL6379054 | 0.80 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1L3MBTL1MAPT | |
| SCHEMBL11801974 | 0.77 | MAPT (0.48) | NPC1RAB9AALDH1A1MAPTATM | |
| SCHEMBL11679299 | 0.73 | L3MBTL1 (0.50) | NPC1RAB9AALDH1A1L3MBTL1MAPT | |
| SCHEMBL4965877 | 0.73 | HRH3 (0.44) | NPC1RAB9A | |
| SCHEMBL5332624 | 0.73 | HRH3 (0.44) | NPC1RAB9A | |
| SCHEMBL11801251 | 0.73 | ALDH1A1 (0.43) | NPC1RAB9AALDH1A1MAPTMEN1 | |
| SCHEMBL11797748 | 0.72 | SLC6A4 (0.46) | ALDH1A1L3MBTL1MAPTCTNNB1WNT3A | |
| SCHEMBL11732460 | 0.72 | MEN1 (0.36) | NPC1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957989-A | ADMINISTERING | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |