Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11550034 | 0.81 | THRA (0.41) | L3MBTL1MAPTNPC1RAB9ATHRA | |
| SCHEMBL11780746 | 0.81 | NPC1 (0.53) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11678405 | 0.80 | NPC1 (0.51) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11677381 | 0.76 | RAB9A (0.50) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL10008853 | 0.75 | HSD17B3 (0.57) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11678301 | 0.75 | L3MBTL1 (0.49) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL21610337 | 0.74 | HSD17B3 (0.58) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL4583779 | 0.74 | HSD17B3 (0.58) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11678331 | 0.74 | THRA (0.49) | L3MBTL1KDM4EMAPTNPC1RAB9A | |
| SCHEMBL11807876 | 0.73 | NPC1 (0.44) | L3MBTL1MAPTNPC1RAB9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064347-A | Bis-basic ketones of fluorene and fluorenone | RICHARDSON-MERRELL INC. (US) | 1977-12-20 | — | — | US | disclosed |