SCHEMBL11808129

SCHEMBL11808129

CC(=O)CC/C=C(/C)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 4/20 0.48
ALDH1A1 P00352 3/20 0.47
MTNR1A P48039 1/20 0.43
MTNR1B P49286 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2D6 P10635 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MAPK1 P28482 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
NR4A2 P43354 1/20 0.39
AKT1 P31749 1/20 0.39
DEGS1 O15121 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25871397 1.00 TBXAS1 (0.48) TBXAS1ALDH1A1MTNR1AMTNR1BCYP1A2
SCHEMBL11808134 1.00 TBXAS1 (0.48) TBXAS1ALDH1A1MTNR1AMTNR1BCYP1A2
SCHEMBL30705332 0.83 KDM1A (0.44) TBXAS1MTNR1AMTNR1BCYP1A2CYP2D6
SCHEMBL11308181 0.83 ALDH1A1 (0.48) ALDH1A1CES2CES1TDP1MAPK1
SCHEMBL27713864 0.81 AKR1C1 (0.47) TBXAS1ALDH1A1MTNR1AMTNR1BCES2
SCHEMBL20471424 0.80 MTNR1A (0.46) TBXAS1ALDH1A1MTNR1AMTNR1BCYP1A2
SCHEMBL28077326 0.80 TBXAS1 (0.43) TBXAS1MTNR1AMTNR1BCYP1A2CYP2D6
SCHEMBL20471425 0.80 MTNR1A (0.46) TBXAS1ALDH1A1MTNR1AMTNR1BCYP1A2
SCHEMBL7714707 0.80 TBXAS1 (0.50) TBXAS1ALDH1A1L3MBTL1MAPTAKT1
SCHEMBL7714709 0.80 TBXAS1 (0.50) TBXAS1ALDH1A1L3MBTL1MAPTAKT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023137133-A2 PROCESS FOR THE SELECTIVE CATALYTIC HYDROGENATION OF DIENONES BASF SE (DE) 2023-07-20 WO disclosed
US-3975446-A FROM UNSATURATED ALCOHOL, TERTIARY AMINE SHINETSU CHEMICAL COMPANY (JA) 1976-08-17 US disclosed