Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 4/20 | 0.50 |
| ▸ | HEXB | P07686 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 7/20 | 0.48 |
| ▸ | HTR7 | P34969 | 6/20 | 0.48 |
| ▸ | HTR1A | P08908 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 6/20 | 0.48 |
| ▸ | HTR6 | P50406 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | AHR | P35869 | 1/20 | 0.45 |
| ▸ | RAD52 | P43351 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11805397 | 0.90 | DRD2 (0.48) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL11804170 | 0.85 | KDM4E (0.51) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL11631639 | 0.78 | L3MBTL1 (0.46) | HEXAHEXBMEN1KMT2AKDM4E | |
| SCHEMBL11807626 | 0.77 | HEXA (0.45) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL11631627 | 0.77 | DRD2 (0.57) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL11806622 | 0.76 | HTR7 (0.58) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL11810138 | 0.76 | HTR7 (0.59) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL11807263 | 0.76 | HTR7 (0.59) | HEXAHEXBDRD2HTR7HTR1A | |
| SCHEMBL9626265 | 0.74 | HEXA (0.83) | HEXAHEXBMEN1KMT2AKDM4E | |
| SCHEMBL11806208 | 0.74 | KDM4E (0.57) | HEXAHEXBDRD2HTR7HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |