Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | HTR6 | P50406 | 4/20 | 0.48 |
| ▸ | HEXA | P06865 | 2/20 | 0.47 |
| ▸ | HEXB | P07686 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.43 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809018 | 0.90 | HEXA (0.50) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL11633643 | 0.79 | L3MBTL1 (0.41) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL11812529 | 0.78 | DRD2 (0.57) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL11804170 | 0.78 | KDM4E (0.51) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL11805624 | 0.78 | HTR7 (0.52) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL11803595 | 0.74 | HTR1A (0.55) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL11807626 | 0.73 | HEXA (0.45) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL22683219 | 0.72 | HEXA (0.73) | HEXAHEXBKDM4EALDH1A1HPGD | |
| SCHEMBL11804223 | 0.72 | HTR1A (0.70) | DRD2HTR1AHTR2AHTR7HTR6 | |
| SCHEMBL9626265 | 0.72 | HEXA (0.83) | HEXAHEXBKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935227-A | ANTIDEPRESSANTS, ANTIANXIETY, ANTIINFLAMMATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |