Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11809146 | 0.82 | FOLH1 (0.42) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL4453278 | 0.80 | TSHR (0.43) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| Sebacic Acid SCHEMBL28583209 | 0.77 | GPR84 (0.44) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL994484 | 0.77 | FFAR4 (0.33) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL2052956 | 0.74 | FFAR4 (0.39) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| Sebacic Acid SCHEMBL8958570 | 0.73 | TSHR (0.56) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL11809257 | 0.72 | DGKA (0.38) | TSHRNFKB1CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL11810335 | 0.71 | DGKA (0.40) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL716438 | 0.71 | TSHR (0.39) | TSHRNFKB1CYP2C19FFAR4FFAR1 | |
| SCHEMBL994483 | 0.70 | TSHR (0.33) | TSHRNFKB1CYP2C19FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344876-A | N-SUBSTITUTED 2,2,6,6-TETRAALYKYL PIPERIDINE PHOTOSTABILIZERS | CIBA-GEIGY CORPORATION (US) | 1982-08-17 | — | — | US | disclosed |