Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 6/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.37 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814488 | 0.93 | MAOB (0.40) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11766849 | 0.90 | LTB4R (0.45) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11767482 | 0.90 | LTB4R (0.45) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11812931 | 0.89 | RAB9A (0.41) | MAPTNPC1RAB9AALDH1A1TTR | |
| SCHEMBL11767315 | 0.89 | LTB4R (0.52) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11767469 | 0.89 | LTB4R (0.48) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11773887 | 0.89 | LTB4R (0.48) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11766512 | 0.89 | LTB4R (0.52) | LTB4RMAPTNPC1RAB9AALDH1A1 | |
| SCHEMBL11813487 | 0.84 | ALDH1A1 (0.38) | LTB4RNPC1RAB9AALDH1A1TTR | |
| SCHEMBL11769105 | 0.84 | LTB4R (0.51) | LTB4RNPC1RAB9ATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951618-A | Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-20 | — | — | US | disclosed |