Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 5/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11811531 | 0.93 | LTB4R (0.45) | LTB4RALDH1A1TTRESR1TSHR | |
| SCHEMBL11812931 | 0.92 | RAB9A (0.41) | MAOBALDH1A1KDM4EPOLBTTR | |
| SCHEMBL11813487 | 0.87 | ALDH1A1 (0.38) | LTB4RALDH1A1KDM4ETTRTSHR | |
| SCHEMBL11766614 | 0.86 | NPC1 (0.40) | ALDH1A1KDM4ETTRLMNANPC1 | |
| SCHEMBL11766849 | 0.85 | LTB4R (0.45) | LTB4RALDH1A1TTRESR1CHRM1 | |
| SCHEMBL11812866 | 0.84 | HSD17B10 (0.37) | LTB4RALDH1A1KDM4ETTRNPC1 | |
| SCHEMBL11770156 | 0.83 | MEN1 (0.42) | MAOBALDH1A1KDM4EPOLBTTR | |
| SCHEMBL11814835 | 0.83 | ALDH1A1 (0.42) | ALDH1A1KDM4EPOLBTTRNPC1 | |
| SCHEMBL11767482 | 0.83 | LTB4R (0.45) | LTB4RALDH1A1TTRESR1TSHR | |
| SCHEMBL11770500 | 0.82 | TTR (0.52) | LTB4RALDH1A1KDM4ETTRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3951618-A | Method of use of, and compositions containing, disubstituted xanthone carboxylic acid compounds | SYNTEX (U.S.A.) INC. (US) | 1976-04-20 | — | — | US | disclosed |