Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 12/20 | 0.53 |
| ▸ | DRD4 | P21917 | 6/20 | 0.53 |
| ▸ | DRD3 | P35462 | 6/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.53 |
| ▸ | HTR2A | P28223 | 3/20 | 0.53 |
| ▸ | HTR2C | P28335 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.51 |
| ▸ | DRD1 | P21728 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11818810 | 0.99 | TSHR (0.57) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL11825274 | 0.91 | TSHR (0.57) | TSHRDRD2DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL11814307 | 0.80 | DRD2 (0.59) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL16986160 | 0.75 | TSHR (0.79) | TSHRDRD2DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL11813998 | 0.75 | ALDH1A1 (0.63) | TSHRDRD2DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL16986146 | 0.74 | TSHR (0.82) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL16986166 | 0.74 | TSHR (0.97) | TSHRDRD2DRD4DRD3HTR1A | |
| SCHEMBL28888225 | 0.74 | THRA (0.64) | TSHRALDH1A1POLBMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11817875 | 0.73 | TSHR (0.54) | TSHRDRD2DRD4DRD3HTR1A | |
| Hydrochloric Acid SCHEMBL16986196 | 0.73 | TSHR (1.00) | TSHRDRD2DRD4DRD3HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3966735-A | CENTRAL NERVOUS SYSTEM | KALI-CHEMIE AKTIENGESELLSCHAFT (DT) | 1976-06-29 | — | — | US | claimed |