Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 4/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.49 |
| ▸ | MTOR | P42345 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11813696 | 0.83 | MAPT (0.52) | MAPTADRB2TSHRKDM4ETDP1 | |
| SCHEMBL11811349 | 0.79 | MAPT (0.54) | MAPTADRB2TSHRKDM4ETDP1 | |
| SCHEMBL11805102 | 0.78 | ADRB2 (0.56) | MAPTADRB2TSHRKDM4ETDP1 | |
| SCHEMBL11807914 | 0.77 | ADRB2 (0.57) | MAPTADRB2TSHRKDM4ETDP1 | |
| SCHEMBL11804077 | 0.77 | ADRB2 (0.55) | MAPTADRB2TSHRKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL11810811 | 0.77 | ADRB2 (0.57) | MAPTADRB2TSHRKDM4ETDP1 | |
| SCHEMBL31585223 | 0.76 | TXNRD1 (0.42) | MAPTTSHRTDP1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11812398 | 0.76 | ADRB2 (0.56) | MAPTADRB2TSHRKDM4ETDP1 | |
| Oxalic Acid SCHEMBL11816918 | 0.75 | MAPT (0.52) | MAPTADRB2TSHRKDM4ETDP1 | |
| Nifenalol SCHEMBL6510064 | 0.75 | NPC1 (0.66) | MAPTADRB2TSHRKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954871-A | ANTIARRHYTHMIA, VASODILATOR, HYPOTENSIVE | CONTINENTAL PHARMA (BE) | 1976-05-04 | — | — | US | disclosed |