Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.42 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.42 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.42 |
| ▸ | PDE7A | Q13946 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16955577 | 0.85 | TXNRD1 (0.41) | TXNRD1TXNRD3TXNRD2PDE7AALDH1A1 | |
| SCHEMBL3874156 | 0.81 | PDE7A (0.58) | TXNRD1TXNRD3TXNRD2PDE7AALDH1A1 | |
| SCHEMBL16959492 | 0.80 | ALDH1A1 (0.42) | TXNRD1TXNRD3TXNRD2ALDH1A1MEN1 | |
| SCHEMBL15927423 | 0.77 | TSHR (0.55) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL16957224 | 0.77 | ADRB2 (0.40) | TXNRD1TXNRD3TXNRD2ALDH1A1MEN1 | |
| SCHEMBL11813689 | 0.76 | MAPT (0.49) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL30155394 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL2698568 | 0.75 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2ACYP3A4TSHR | |
| SCHEMBL8973665 | 0.75 | TXNRD1 (0.72) | TXNRD1TXNRD3TXNRD2ALDH1A1MEN1 | |
| SCHEMBL8150935 | 0.75 | PDK1 (0.41) | ALDH1A1MEN1KMT2ACYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106383-A1 | PYRROLIDINYL DERIVATIVES USEFUL AS HCN1/HCN 2 MODULATORS | MERCK SHARP & DOHME LLC (US) | 2025-05-22 | — | — | WO | disclosed |