Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 6/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.35 |
| ▸ | WNT3A | P56704 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11676745 | 0.72 | RAB9A (0.50) | ALDH1A1KDM4EHSD17B3SMN1; SMN2LMNA | |
| SCHEMBL11819666 | 0.72 | HPGD (0.40) | HPGDATMCTNNB1WNT3A | |
| SCHEMBL11819443 | 0.72 | THRA (0.48) | HPGDALDH1A1CTNNB1WNT3AMAPT | |
| SCHEMBL11817359 | 0.71 | CTNNB1 (0.39) | HPGDALDH1A1CTNNB1WNT3ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL11678025 | 0.71 | RAB9A (0.49) | ALDH1A1KDM4EHSD17B3SMN1; SMN2LMNA | |
| SCHEMBL14141221 | 0.71 | HTR7 (0.67) | ALDH1A1KDM4EHSD17B3SMN1; SMN2LMNA | |
| SCHEMBL10214294 | 0.71 | ATM (0.50) | HPGDALDH1A1KDM4EATMCTNNB1 | |
| Hydrochloric Acid SCHEMBL11819328 | 0.71 | HPGD (0.39) | HPGDATMCTNNB1WNT3ASMN1; SMN2 | |
| SCHEMBL10170811 | 0.71 | ALDH1A1 (0.42) | HPGDALDH1A1KDM4EATMCTNNB1 | |
| SCHEMBL11746200 | 0.69 | ALDH1A1 (0.54) | HPGDALDH1A1KDM4ETP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3937835-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |