Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KLK8 | O60259 | 1/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11390684 | 0.84 | ELANE (0.45) | NPSR1MEN1LMNARECQLKMT2A | |
| SCHEMBL11388122 | 0.82 | MEN1 (0.43) | NPSR1MEN1LMNARECQLKMT2A | |
| SCHEMBL11815209 | 0.78 | ELANE (0.38) | NPSR1MEN1LMNARECQLKMT2A | |
| SCHEMBL10459006 | 0.75 | MEN1 (0.44) | NPSR1MEN1LMNARECQLKMT2A | |
| SCHEMBL11795463 | 0.72 | RAB9A (0.43) | MEN1KMT2AKLK1ELANEF2 | |
| SCHEMBL5968318 | 0.67 | L3MBTL1 (0.54) | LMNAKMT2ATDP1ESR1ESR2 | |
| SCHEMBL11390682 | 0.64 | ELANE (0.50) | NPSR1MEN1LMNARECQLKMT2A | |
| SCHEMBL6375764 | 0.63 | ESR1 (0.52) | NPSR1LMNAKMT2ASRCESR1 | |
| SCHEMBL6377979 | 0.63 | ESR1 (0.52) | NPSR1LMNAKMT2ASRCESR1 | |
| SCHEMBL1905659 | 0.63 | NPSR1 (0.58) | NPSR1MEN1LMNARECQLKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258040-A | Cephalosporin compounds | MERCK & CO., INC. (US) | 1981-03-24 | — | — | US | disclosed |
| US-4060687-A | Cephalosporins having a 3-α substituted alkyl grouping | MERCK & CO., INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-3947413-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1976-03-30 | — | — | US | disclosed |