Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11375460 | 0.84 | ALDH1A1 (0.63) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11816205 | 0.79 | KDM5A (0.47) | ALDH1A1KDM4EKMT2ALMNAMEN1 | |
| SCHEMBL11815260 | 0.74 | LMNA (0.53) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11377101 | 0.74 | ALDH1A1 (0.51) | ALDH1A1KDM4ESMN1; SMN2HTTLMNA | |
| SCHEMBL11383580 | 0.73 | ALDH1A1 (0.67) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A | |
| SCHEMBL11377362 | 0.72 | ALDH1A1 (0.67) | ALDH1A1KDM4ESMN1; SMN2KMT2AHTT | |
| SCHEMBL11812543 | 0.71 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2KMT2AHTT | |
| SCHEMBL11821942 | 0.71 | NPSR1 (0.47) | ALDH1A1KDM4ESMN1; SMN2KMT2APOLB | |
| SCHEMBL11816514 | 0.71 | ALDH1A1 (0.65) | ALDH1A1KDM4ESMN1; SMN2KMT2AHTT | |
| SCHEMBL11638740 | 0.71 | ALDH1A1 (0.46) | ALDH1A1KDM4ETSHRSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3960868-A | Derivatives of 6,7 or 8 cycloalkyl 4-oxo quinoline 3 carboxylic acid | CIBA-GEIGY CORPORATION (US) | 1976-06-01 | — | — | US | disclosed |