Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.30 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11806977 | 0.79 | HSD11B1 (0.34) | KDM4EKMT2A | |
| SCHEMBL11814233 | 0.78 | XPO1 (0.30) | — | |
| SCHEMBL11814904 | 0.75 | ABL1 (0.33) | KMT2A | |
| SCHEMBL11812366 | 0.74 | ADRB2 (0.30) | — | |
| SCHEMBL11517572 | 0.73 | KDM4E (0.40) | KDM4EKMT2A | |
| SCHEMBL11810909 | 0.72 | GRM2 (0.35) | — | |
| SCHEMBL11811536 | 0.72 | — | — | |
| SCHEMBL11807421 | 0.72 | DPP4 (0.39) | — | |
| SCHEMBL11806966 | 0.72 | TLR7 (0.31) | — | |
| SCHEMBL11817465 | 0.72 | ADORA2A (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |