Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 9/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | COMT | P21964 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11814904 | 0.82 | ABL1 (0.33) | NOTUMKMT2AABL1 | |
| SCHEMBL11812544 | 0.82 | — | — | |
| SCHEMBL11809102 | 0.82 | CSNK1E (0.36) | DYRK1AABL1 | |
| SCHEMBL11517572 | 0.82 | KDM4E (0.40) | CDK9DYRK1AKDM4EALDH1A1LMNA | |
| SCHEMBL11812486 | 0.81 | KMT2A (0.33) | CDK9DYRK1AMEN1PKMKMT2A | |
| SCHEMBL11805651 | 0.80 | CDK9 (0.40) | CDK9DYRK1AKDM4EALDH1A1HPGD | |
| SCHEMBL11811404 | 0.80 | HSD11B1 (0.35) | HSD11B1CDK9DYRK1A | |
| SCHEMBL11810979 | 0.80 | CDK9 (0.40) | CDK9DYRK1AKDM4EALDH1A1PKM | |
| SCHEMBL11804036 | 0.79 | TLR8 (0.38) | CDK9DYRK1AHPGDMEN1PKM | |
| SCHEMBL11804027 | 0.79 | DHFR (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954438-A | 5-Trifluoromethyl-7-aminobenzimidazoles herbicides | UNITED STATES BORAX & CHEMICAL CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |