Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PTPRG | P23470 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | RHEB | Q15382 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11819833 | 0.80 | KMT2A (0.52) | MEN1KMT2AHPGDMAPTRAB9A | |
| SCHEMBL11815653 | 0.80 | LMNA (0.56) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL15819764 | 0.79 | SIRT2 (0.58) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL4551075 | 0.79 | MEN1 (0.64) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL11816323 | 0.76 | ALDH1A1 (0.46) | LMNAALDH1A1DAOMRGPRX4 | |
| SCHEMBL11820343 | 0.74 | MRGPRX4 (0.54) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL11821792 | 0.73 | MAPT (0.48) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL23012753 | 0.72 | PTGDR2 (0.51) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL29691413 | 0.72 | PTGDR2 (0.51) | MEN1KMT2ALMNAHPGDMAPT | |
| SCHEMBL3889931 | 0.72 | MAOB (0.54) | MEN1KMT2ALMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |