Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815267 | 0.85 | KMT2A (0.47) | ALDH1A1MAPTCYP3A4CYP2C19MEN1 | |
| SCHEMBL6794925 | 0.83 | ALDH1A1 (0.51) | ALDH1A1MAPTCYP3A4CYP2C19MEN1 | |
| SCHEMBL11814074 | 0.78 | TP53 (0.56) | ALDH1A1MAPTCYP3A4CYP2C19MEN1 | |
| SCHEMBL11819492 | 0.77 | DAO (0.43) | ALDH1A1DAOHPGDPOLB | |
| SCHEMBL11821792 | 0.75 | MAPT (0.48) | ALDH1A1MAPTCYP3A4CYP2C19MEN1 | |
| SCHEMBL15054482 | 0.75 | MAPT (0.62) | MAPTCYP3A4MEN1KMT2ATP53 | |
| SCHEMBL11816111 | 0.75 | TP53 (0.43) | ALDH1A1MAPTCYP3A4CYP2C19MEN1 | |
| SCHEMBL11815968 | 0.75 | MAPT (0.45) | ALDH1A1MAPTMEN1KMT2ATP53 | |
| SCHEMBL11817074 | 0.74 | DAO (0.41) | ALDH1A1MAPTDAOHPGDSMN1; SMN2 | |
| SCHEMBL6790960 | 0.73 | KMT2A (0.58) | ALDH1A1MAPTCYP3A4CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |