Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11816372 | 0.81 | TP53 (0.48) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11823158 | 0.80 | POLB (0.47) | TDP1MEN1KMT2ASMN1; SMN2SRD5A2 | |
| SCHEMBL11819247 | 0.78 | MMP1 (0.41) | TDP1MEN1KMT2ASRD5A2ALDH1A1 | |
| SCHEMBL11820906 | 0.75 | ALDH1A1 (0.47) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11816111 | 0.73 | TP53 (0.43) | TDP1MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11819408 | 0.72 | PKM (0.48) | TDP1MEN1KMT2ASMN1; SMN2SRD5A2 | |
| SCHEMBL11828341 | 0.72 | NR4A2 (0.46) | MEN1KMT2ASRD5A2MAPTP2RY14 | |
| SCHEMBL265084 | 0.71 | TSHR (0.63) | TDP1MEN1KMT2ASMN1; SMN2SRD5A2 | |
| SCHEMBL11818098 | 0.70 | NR4A2 (0.44) | MEN1KMT2ASRD5A2LMNAMAPT | |
| SCHEMBL20826098 | 0.70 | TPMT (0.61) | TDP1MEN1KMT2ASMN1; SMN2SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |