Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820801 | 0.81 | NPC1 (0.45) | KMT2AMEN1HTTMAPTMRGPRX4 | |
| SCHEMBL11816320 | 0.80 | MEN1 (0.49) | KMT2AMEN1MAPTMRGPRX4SMN1; SMN2 | |
| SCHEMBL11819309 | 0.79 | ALDH1A1 (0.43) | KMT2AMEN1HTTMAPTPTGDR2 | |
| SCHEMBL11816193 | 0.79 | KMT2A (0.44) | KMT2AMEN1HTTMAPTSMN1; SMN2 | |
| SCHEMBL11819838 | 0.77 | MRGPRX4 (0.52) | KMT2AMEN1MAPTMRGPRX4RAB9A | |
| SCHEMBL16143105 | 0.76 | HTT (0.54) | KMT2AMEN1HTTMAPTPTGDR2 | |
| SCHEMBL11815274 | 0.76 | MRGPRX4 (0.53) | KMT2AMEN1HTTMAPTMRGPRX4 | |
| SCHEMBL12581571 | 0.75 | APEX1 (0.65) | HTTMAPTMRGPRX4SMN1; SMN2AR | |
| SCHEMBL23012753 | 0.75 | PTGDR2 (0.51) | KMT2AMEN1HTTMAPTPTGDR2 | |
| SCHEMBL29691413 | 0.75 | PTGDR2 (0.51) | KMT2AMEN1HTTMAPTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |