Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11866467 | 0.82 | KCNH2 (0.44) | OPRM1SIGMAR1BCHEDRD2SLC6A2 | |
| SCHEMBL11805088 | 0.82 | OPRK1 (0.36) | OPRM1OPRD1OPRK1SIGMAR1BCHE | |
| SCHEMBL11867678 | 0.81 | KCNH2 (0.40) | SIGMAR1DRD2SLC6A2HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL11859118 | 0.81 | KCNH2 (0.43) | OPRM1SIGMAR1BCHEDRD2SLC6A2 | |
| SCHEMBL11862034 | 0.79 | SIGMAR1 (0.47) | OPRM1OPRK1SIGMAR1DRD2SLC6A2 | |
| Hydrochloric Acid SCHEMBL11862820 | 0.78 | SIGMAR1 (0.46) | SIGMAR1DRD2SLC6A2HTR2AHTR2C | |
| SCHEMBL11816570 | 0.76 | KDM4E (0.34) | SIGMAR1 | |
| SCHEMBL11750577 | 0.74 | HTR2A (0.36) | DRD2SLC6A2HTR2AHTR2CSLC6A4 | |
| SCHEMBL11840137 | 0.72 | OPRM1 (0.39) | OPRM1OPRD1OPRK1SIGMAR1BCHE | |
| SCHEMBL11800049 | 0.69 | HTR2A (0.46) | OPRM1OPRD1OPRK1SIGMAR1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | claimed |
| US-3957988-A | Antiviral compositions containing bis-basic ketones of thioxanthene | RICHARDSON-MERRELL INC. (US) | 1976-05-18 | — | — | US | disclosed |
| US-3937835-A | DELAYED HYPERSENSITIVITY | RICHARDSON-MERRELL INC. (US) | 1976-02-10 | — | — | US | disclosed |