Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11815191 | 0.88 | TSHR (0.53) | HSD17B10TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL11817298 | 0.86 | TDP1 (0.58) | HSD17B10TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL11817881 | 0.82 | L3MBTL1 (0.59) | HSD17B10TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL11818707 | 0.80 | CYP3A4 (0.62) | HSD17B10TSHRCYP3A4MAPTL3MBTL1 | |
| SCHEMBL11817749 | 0.77 | PTPRG (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL11821935 | 0.74 | L3MBTL1 (0.60) | HSD17B10TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL1000486 | 0.72 | POLB (0.74) | HSD17B10TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL1708867 | 0.72 | TSHR (1.00) | HSD17B10TSHRCYP3A4ALDH1A1MAPT | |
| SCHEMBL11819446 | 0.71 | CYP3A4 (0.59) | HSD17B10TSHRCYP3A4MAPTL3MBTL1 | |
| SCHEMBL11822430 | 0.71 | ALDH1A1 (0.54) | CYP3A4ALDH1A1MAPTHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |