Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817881 | 0.93 | L3MBTL1 (0.59) | L3MBTL1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11820807 | 0.80 | TDP1 (0.56) | L3MBTL1MEN1KMT2APTPRCMAPT | |
| SCHEMBL11822234 | 0.80 | L3MBTL1 (0.57) | L3MBTL1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL11819446 | 0.80 | CYP3A4 (0.59) | L3MBTL1TSHRMEN1KMT2ACYP3A4 | |
| SCHEMBL11820641 | 0.75 | AKR1C3 (0.52) | PTPRCLMNAMAPT | |
| SCHEMBL11565647 | 0.75 | AR (0.64) | KMT2APTPRCHTT | |
| SCHEMBL11817067 | 0.74 | HSD17B10 (0.58) | L3MBTL1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL13802463 | 0.74 | PTPRG (0.70) | L3MBTL1MEN1KMT2APTPRCGAA | |
| SCHEMBL11815191 | 0.73 | TSHR (0.53) | L3MBTL1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL1708867 | 0.73 | TSHR (1.00) | L3MBTL1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |