Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | IL1RN | P18510 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11817067 | 0.88 | HSD17B10 (0.58) | TSHRHSD17B10CYP3A4KMT2AMEN1 | |
| SCHEMBL11817298 | 0.85 | TDP1 (0.58) | TSHRHSD17B10CYP3A4KMT2AMEN1 | |
| SCHEMBL11817881 | 0.81 | L3MBTL1 (0.59) | TSHRHSD17B10CYP3A4KMT2AMEN1 | |
| SCHEMBL11818707 | 0.78 | CYP3A4 (0.62) | TSHRHSD17B10CYP3A4KMT2AMEN1 | |
| SCHEMBL11821552 | 0.78 | CA2 (0.42) | ALDH1A1 | |
| SCHEMBL11817140 | 0.78 | CA2 (0.42) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL11823574 | 0.74 | MAPT (0.44) | KMT2AMEN1TP53POLBMAPT | |
| SCHEMBL11821935 | 0.73 | L3MBTL1 (0.60) | TSHRHSD17B10CYP3A4KMT2AMEN1 | |
| SCHEMBL11819740 | 0.72 | VCAM1 (0.40) | TSHRL3MBTL1MAPTALDH1A1NPSR1 | |
| SCHEMBL11823057 | 0.72 | ALDH1A1 (0.41) | POLBMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |