Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 4/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043663 | 0.85 | IDO1 (0.49) | ALDH1A1NPC1RAB9ATDP1KDM4E | |
| SCHEMBL31582715 | 0.81 | KDM4E (0.54) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL15359911 | 0.81 | KDM4E (0.54) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| Hydrochloric Acid SCHEMBL20771312 | 0.79 | KDM4E (0.53) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL29043661 | 0.79 | ALDH1A1 (0.48) | ALDH1A1NPC1RAB9ATDP1GAA | |
| SCHEMBL2723179 | 0.77 | ALDH1A1 (0.57) | ALDH1A1NPC1RAB9ATDP1HSD17B10 | |
| SCHEMBL3996398 | 0.76 | L3MBTL1 (0.57) | ALDH1A1HSD17B10KDM4EMAPTLMNA | |
| SCHEMBL5258681 | 0.76 | HSPB1 (0.45) | ALDH1A1GAAKDM4EGLAMAPT | |
| SCHEMBL20870396 | 0.74 | KDM4E (0.45) | ALDH1A1HSD17B10CFTRGAAKDM4E | |
| SCHEMBL16792635 | 0.74 | UHRF1 (0.46) | ALDH1A1NPC1RAB9AHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069957-B | Prolyl hydroxylase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |