Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29043665 | 0.85 | ALDH1A1 (0.58) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL29589415 | 0.77 | NNMT (0.51) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL2002960 | 0.77 | NNMT (0.51) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16792635 | 0.76 | UHRF1 (0.46) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL16792623 | 0.75 | SMN1; SMN2 (0.46) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11817548 | 0.74 | ACACB (0.42) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL5078313 | 0.73 | POLB (0.57) | IDO1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL14015136 | 0.72 | LOXL2 (0.45) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11812772 | 0.72 | MAPT (0.45) | NPC1RAB9AMEN1KMT2AALDH1A1 | |
| SCHEMBL11817553 | 0.72 | CCNC (0.43) | NPC1RAB9AMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108069957-B | Prolyl hydroxylase inhibitors and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |