Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.38 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 4/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.37 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11820227 | 0.87 | TRPV1 (0.46) | MRGPRX4AURKATPX2PPARAALDH1A1 | |
| SCHEMBL11820243 | 0.84 | MRGPRX4 (0.48) | MRGPRX4AURKATPX2PPARAPPARG | |
| SCHEMBL11819492 | 0.82 | DAO (0.43) | DAOMRGPRX4PPARAPPARGPPARD | |
| SCHEMBL11815385 | 0.76 | MRGPRX4 (0.46) | MRGPRX4AURKATPX2PPARAALDH1A1 | |
| SCHEMBL11818774 | 0.74 | ALDH1A1 (0.46) | DAOALDH1A1HPGDMAPTSMN1; SMN2 | |
| SCHEMBL11818108 | 0.73 | PTPRZ1 (0.40) | MRGPRX4AURKATPX2PPARAHPGD | |
| SCHEMBL11818815 | 0.73 | MRGPRX4 (0.42) | MRGPRX4AURKATPX2ALDH1A1HPGD | |
| SCHEMBL24017339 | 0.71 | KCNK2 (0.48) | MRGPRX4AURKATPX2PPARAMAPT | |
| SCHEMBL475754 | 0.70 | AURKA (0.56) | MRGPRX4AURKATPX2PPARAALDH1A1 | |
| SCHEMBL31550001 | 0.70 | AURKA (0.56) | MRGPRX4AURKATPX2PPARAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954994-A | Intermediates for preparing hipolipemic agents and method of lowering the blood lipid level in mammals with said agents | PFIZER INC. (US) | 1976-05-04 | — | — | US | disclosed |